The Upper Mississippi River, often referred to as the “Father of Waters,” is one of the most iconic waterways in the United States, winding its way through the heart of the Midwest. Stretching approximately 1,200 miles from its source at Lake Itasca in Minnesota to the confluence with the Ohio River in Illinois, this majestic river offers a unique blend of natural beauty, rich history, and vibrant culture, making it a sought-after destination for river cruises.
The Upper Mississippi River is renowned for its stunning landscapes, characterized by rolling hills, lush forests, and picturesque bluffs that rise dramatically along the riverbanks. The region is home to a diverse array of wildlife, providing ample opportunities for birdwatching and nature photography. The river’s meandering course creates a peaceful ambiance, perfect for leisurely cruising. Travelers can enjoy breathtaking sunsets and tranquil mornings, all while being surrounded by the serene waters and charming small towns that dot the river’s edge.
If you’re looking for an unforgettable vacation immersed in natural beauty, historic landmarks, and small-town charm, an Upper Mississippi River cruise is the perfect choice.
Why Choose an Upper Mississippi River Cruise?
Choosing a cruise along the Upper Mississippi is more than just a trip—it’s a journey through America’s heartland. Unlike the Lower Mississippi, which features larger cities like New Orleans and Memphis, the Upper Mississippi is known for its tranquil river towns, breathtaking natural beauty, and fascinating history. These cruises allow you to:
Reconnect with Nature: The Upper Mississippi River boasts stunning vistas of lush forests, rolling hills, and wildlife sanctuaries. It’s a great place for birdwatching, especially for spotting bald eagles.
Explore American History: This region played a pivotal role in America’s development. From the early days of European settlers to the era of steamboats, a cruise along the Upper Mississippi is like stepping back in time.
Experience Small-Town Charm: Stops in quaint towns like Hannibal, La Crosse, and Dubuque provide a taste of authentic Midwestern hospitality. These towns are often rich in local history, food, and culture, giving travelers a unique and immersive experience.
Relax in Comfort: River cruises tend to be more laid-back than ocean cruises. They focus more on relaxation and enrichment, making them ideal for travelers who want to unwind while still learning about the areas they visit.
When to Take an Upper Mississippi River Cruise?
The best time to cruise the Upper Mississippi is typically between late spring and early fall (May through October). The weather is pleasant, and the landscapes are at their most vibrant, particularly during autumn when the fall foliage along the river is breathtaking. Peak season generally falls in the summer months, but the mild temperatures in spring and fall can provide a more peaceful and less crowded experience.
Best Upper Mississippi River Cruises:
1. American Serenade Cruise
The American Serenade Cruise is a luxurious 8-night journey along the Upper Mississippi that offers a perfect blend of relaxation, history, and stunning natural beauty. Operated by American Cruise Lines, the American Serenade is a modern, elegant riverboat that provides guests with first-class amenities, spacious cabins, and exceptional dining.
Duration: 8 nights / 9 days
Starting Price: From $5,295 per person (prices vary depending on the season and cabin type)
Itinerary:
Day 1: Departure from St. Paul, Minnesota
Day 2: Red Wing, Minnesota (Explore historic downtown and antique shops)
Day 3: La Crosse, Wisconsin (Visit the Dahl Auto Museum and Grandad Bluff)
Day 4: Dubuque, Iowa (Tour the National Mississippi River Museum & Aquarium)
Day 5: Davenport, Iowa (Explore the Figge Art Museum and Village of East Davenport)
Day 6: Burlington, Iowa (Learn about the local history and visit Snake Alley)
Day 7: Hannibal, Missouri (Explore Mark Twain’s boyhood home and museum)
Day 8: St. Louis, Missouri (Tour the Gateway Arch and Old Courthouse)
Day 9: Disembark in St. Louis, Missouri
Highlights:
Luxury Riverboat Experience: The American Serenade offers a modern, luxurious experience with spacious staterooms, private balconies, and elegant common areas.
Historic Sites: Explore the rich history of the Mississippi River, from Civil War-era landmarks to charming riverfront towns.
Natural Beauty: The scenic views from the ship’s deck are breathtaking, especially as the cruise passes through the limestone bluffs and rolling hills of the Upper Mississippi.
Related: The 10 Best U.S. River Cruises for Seniors
2. American Heritage cruise
The American Heritage Cruise—formerly known as the Queen of the Mississippi—offers a classic river cruise experience focusing on American history and culture. This cruise, also operated by American Cruise Lines, takes you through the Upper Mississippi River, visiting iconic towns and historic sites along the way.
Duration: 7 nights / 8 days
Starting Price: From $4,295 per person (prices vary depending on the season and cabin type)
Itinerary:
Day 1: Departure from St. Louis, Missouri
Day 2: Hannibal, Missouri (Tour Mark Twain’s boyhood home and museum)
Day 3: Fort Madison, Iowa (Visit the historic fort and local museums)
Day 4: Dubuque, Iowa (Explore the National Mississippi River Museum & Aquarium)
Day 5: La Crosse, Wisconsin (Tour the Riverside Museum and Dahl Auto Museum)
Day 6: Red Wing, Minnesota (Antique shopping and visit to the Red Wing Shoe Museum)
Day 7: St. Paul, Minnesota (Explore downtown and the state capitol)
Day 8: Disembark in St. Paul, Minnesota
Highlights:
Classic Paddlewheel Experience: The American Heritage is a traditional paddlewheel ship, providing a nostalgic and charming river cruise experience reminiscent of the early steamboat days.
Cultural Excursions: Guests can enjoy a range of excursions, from visiting Civil War battlefields to exploring local museums and art galleries in charming river towns.
Onboard Entertainment: The cruise features nightly entertainment, including live performances that celebrate the music and stories of the Mississippi River.
Educational Programs: Onboard historians and guest speakers provide insights into the river’s history, its role in shaping America, and the historical significance of each port of call.
3. Heartland of America Cruise
The Heartland of America Cruise aboard the Viking Mississippi is an unforgettable journey through the heart of the United States, offering a seamless blend of luxury, education, and exploration. Operated by Viking River Cruises, this cruise is designed for travelers who want to experience the rich history and natural beauty of the Upper Mississippi in style.
Duration: 7 nights / 8 days
Starting Price: From $4,999 per person (prices vary depending on the season and cabin type)
Itinerary:
Day 1: Departure from St. Paul, Minnesota (Explore the Minnesota State Capitol and Cathedral of St. Paul)
Day 2: Red Wing, Minnesota (Visit Barn Bluff and the Red Wing Shoe Museum)
Day 3: La Crosse, Wisconsin (Tour Riverside Museum and hike Grandad Bluff)
Day 4: Dubuque, Iowa (Explore the National Mississippi River Museum & Aquarium)
Day 5: Burlington, Iowa (Stroll through historic downtown and visit Snake Alley)
Day 6: Hannibal, Missouri (Discover Mark Twain’s heritage and local landmarks)
Day 7: St. Louis, Missouri (Tour the Gateway Arch and visit the Missouri History Museum)
Day 8: Disembark in St. Louis, Missouri
Highlights:
Viking Luxury: The Viking Mississippi offers a sophisticated, Scandinavian-inspired aesthetic, with spacious staterooms, private verandas, and world-class dining that reflects the region’s flavors.
Cultural Enrichment: Viking’s cruises are known for their educational focus, and the Heartland of America cruise is no exception.
Scenic Stops: From the historic town of Red Wing, Minnesota, to the rolling hills of Dubuque, Iowa, this cruise offers a variety of scenic and cultural highlights that showcase the charm of the Midwest.
World-Class Service: Viking is known for its attentive service, with a crew that goes above and beyond to ensure a memorable experience.
Related: The 9 best Mississippi River cruises for seniors
4. American Melody Cruise
The American Melody Cruise, operated by American Cruise Lines, is a modern riverboat experience that combines luxury, comfort, and exploration. The American Melody is known for its contemporary design, spacious staterooms, and environmentally conscious amenities.
Duration: 7 nights / 8 days
Starting Price: From $4,725 per person (prices vary depending on the season and cabin type)
Itinerary:
Day 1: Departure from St. Louis, Missouri (Explore the Gateway Arch and historic riverfront)
Day 2: Hannibal, Missouri (Visit Mark Twain’s boyhood home and museum)
Day 3: Fort Madison, Iowa (Explore the Old Fort Madison and local museums)
Day 4: Davenport, Iowa (Tour the Figge Art Museum and the historic Village of East Davenport)
Day 5: Dubuque, Iowa (Visit the National Mississippi River Museum & Aquarium)
Day 6: La Crosse, Wisconsin (Take in views from Grandad Bluff and tour the Dahl Auto Museum)
Day 7: Red Wing, Minnesota (Explore Barn Bluff and browse antiques in historic downtown)
Day 8: Disembark in St. Paul, Minnesota
Highlights:
Modern Luxury: The American Melody is a state-of-the-art riverboat, offering spacious staterooms, private balconies, and panoramic views from the ship’s lounges and observation decks.
Cultural Immersion: From the Figge Art Museum in Davenport to the National Mississippi River Museum in Dubuque, each stop offers a deep dive into local culture and history.
Scenic Beauty: The Upper Mississippi is known for its stunning landscapes, including towering bluffs, rolling hills, and wildlife-rich riverbanks. Enjoy these views from the comfort of the ship’s deck or during guided nature excursions.
5. American Symphony Cruise
The American Symphony Cruise, operated by American Cruise Lines, is a luxury riverboat experience that brings modern elegance to the Upper Mississippi. The American Symphony is one of the newest ships in the fleet, offering spacious staterooms, private balconies, and excellent onboard amenities.
Duration: 7 nights / 8 days
Starting Price: From $4,995 per person (prices vary depending on the season and cabin type)
Itinerary:
Day 1: Departure from St. Louis, Missouri (Explore the Gateway Arch and the Missouri History Museum)
Day 2: Hannibal, Missouri (Visit Mark Twain’s boyhood home and museum)
Day 3: Fort Madison, Iowa (Tour Old Fort Madison and explore the local museums)
Day 4: Davenport, Iowa (Visit the Figge Art Museum and stroll through the historic Village of East Davenport)
Day 5: Dubuque, Iowa (Explore the National Mississippi River Museum & Aquarium)
Day 6: La Crosse, Wisconsin (Visit Grandad Bluff and the Dahl Auto Museum)
Day 7: Red Wing, Minnesota (Tour Barn Bluff and browse antiques in historic downtown)
Day 8: Disembark in St. Paul, Minnesota
Highlights:
Modern Luxury: The American Symphony offers a sleek, contemporary design with luxurious staterooms, private balconies, and large observation decks that provide panoramic views of the Mississippi River.
Small-Town Charm: Stops in towns like Hannibal and Red Wing allow passengers to explore quaint, historic river towns that played pivotal roles in shaping American culture.
Mark Twain’s Hannibal: A visit to Hannibal, Missouri, lets you delve into the world of Mark Twain, with tours of his boyhood home and museum, gaining insight into the famed author’s life and works.
Scenic River Views: The cruise offers breathtaking views of the Upper Mississippi’s natural beauty, including limestone bluffs, rolling farmlands, and wildlife along the riverbanks.
Local Culture: In places like Davenport and La Crosse, explore local art, history, and cuisine, providing a deeper understanding of the Midwest’s cultural landscape.